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Aerial view of UCSD campus looking South

Geisel Library - Nobel Laureates at UCSD

Discovery of new atmospheric reaction garners prize

Urey Hall Addition

Pacific Hall

Natural Sciences Building

The crystal structure of a group II intron in the pre-catalytic state

Geisel Library Walk

York Hall

Structure of an inhibitor of hepatitis C virus protein synthesis bound to its target in the viral ribonucleic acid (RNA) genome

ANCA probe staining amyloid plaques derived from Alzheimer’s-related Aβ peptides fluoresces as green and as yellow when derived from prion proteins (PrPSC)

Price Center

Generation of bio-resistive surface coatings on amyloids inhibits harmful protein-amyloid interactions associated with Alzheimer disease

Proposed schematic models of the interfacial binding surface of four different members of the Phospholipase A2 superfamily

Urey Hall and Pacific Hall

Characterization of the "inhibitor binding pocket" in the catalytic domain of the calcium-independent phospholipase A2 with residues within a 5 A raidus of the inhibitor shown

A Crystalline Singlet Phosphinonitrene: a Nitrogen Atom Transfer Agent

Mayer Hall

Drug candidate in orange envelope bound to UPPS

Possible binding modes for phospholipase A2 via its membrane interaction site, another allosteric site, and its catalytic site



News

Nobel Laureate, Mario Molina is Awarded the UCSD Medal
Distinguished Professor Mario Molina was presented with the UCSD Medal in acknowledgment of his work in Climate Change Science. Prof. Molinas research has been invaluable in the ongoing research on climate change. His leadership has also laid the path for integrating Science and social responsibility for the changes in our climate.

Professor Michael Sailor Contributes to Pacific Northwest National Labs Project
Professor Michael Sailor contributes his expertise to the Pacific Northwest National Lab (PPNL) led project to increase battery storage capacity in laptops, and other electric devices. The project led by PNNL used Prof. Sailors method of creating a porous silicon by placing thin sheets in a chemical bath to carve our tiny holes throughout the material and then coating the result with a thin layer of conductive carbon to make their electrodes.

2013-14 Kamen Prize Awarded to Dr. Miao-Ping Chien
The Department of Chemistry & Biochemistry proudly announces this years recipient of the 2013-14 Kamen Prize  Dr. Miao-Ping Chien from the Gianneschi Lab for her dissertation entitled Programming nanoparticles with DNA, peptides and enzymes.

Prof. Kimberly Prather Selected as a 2014 Faculty Research Lecturer Award

Stacey Brydges and Robert Ternansky win 2013/14 Distinguished Teaching Award
Dr. Stacey Brydges , LPSOE, and Dr. Robert Ternansky, Lecturer, have been selected by the Academic Senate Committee on Distinguished Teaching to receive a 2013/2014 Distinguished Teaching Award.

American Academy of Arts and Sciences Elects Distinguished Professor Clifford Kubiak
The Department of Chemistry & Biochemistry is proud to announce that distinguished Professor Clifford Kubiak has been elected to the American Academy of Arts and Sciences! As one of the nations most prestigious honor societies it honors accomplished leaders from academe, business, public affairs, the humanities and the arts.

Chemistry and Biochemistry Student Awarded NSF Graduate Research Fellowship
We proudly announce that the National Science Foundation has selected Andrea Carlini from the Gianneschi Lab here at the Department of Chemistry and Biochemistry to receive the 2014 Graduate Research Fellowship!

Eric Chen wins the Intel Science Talent Search
Eric Chen, a senior at Canyon Crest Academy and a volunteer in the lab of Prof. Rommie Amaro, won the top award in the prestigious Intel Science Talent Search contest along with $100,000 in scholarship money with his research into potential new drugs to prevent influenza outbreaks. Sometimes called the high school version of the Nobel Prize, the Intel science talent search is one of the oldest and most prestigious pre-college national science and math competition in the country. This years competition attracted nearly 1,800 entries. Chen was recently interviewed by Channel 8.

Why Distant Dust Storms Matter to California Rainfall
A recent KQED radio interview explaining why distant dust storms matter to California rainfall was given by UC San Diego Distinguished Chair in Atmospheric Chemistry Kimberly Prather, Bill Lapenta, who runs the weather forecasting division of the National Weather Service, and Marty Ralph, Director of the Center for Western Weather and Water Extremes at the Scripps Institution of Oceanography. Scientists are trying to understand why some storms unload lots of rain and snow in California and others don't. Theyre finding it could be linked to dust storms thousands of miles away.

Dean Thiemens awarded Albert Einstein Professorship from the Chinese Academy of Sciences
Distinguished Professor Mark Thiemens, Dean of the Physical Sciences Division, has been selected to receive an Albert Einstein Visiting Professorship from the Chinese Academy of Sciences. It is one of the People's Republic of China's highest awards. It is given to those working at the very frontiers of science. Other recipients this year include Professors Martin Karplus, Robert Grubbs, and K.C. Nicolau. The award will include giving lectures in several cities in China.

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Message from the Chair

Seth M. Cohen, Chair



Faculty Spotlight

View profile for Kim Albizati
Kim Albizati

Chemical Education                                                 

View profile for Rommie Amaro
Rommie Amaro

Computational Chemistry and Biophysics

View profile for Timothy Baker
Timothy Baker

Macromolecular, cryoelectron microscopy and three-dimensional, image-reconstruction techniques.

View profile for Timothy Bertram
Timothy Bertram

Experimental Atmospheric Chemistry

View profile for Guy Bertrand
Guy Bertrand

                                                 

View profile for Stacey Brydges
Stacey Brydges

Chemical Education: Development of context-rich curriculum; Use of collaborative learning strategies in large lectures; Communication of chemistry

View profile for Michael Burkart
Michael Burkart

Natural product synthesis/biosynthesis, Biological chemistry and enzymology, Metabolic engineering.

View profile for Seth Cohen
Seth Cohen

Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materials.

View profile for Robert Continetti
Robert Continetti

Dissociation dynamics of transient species, three-body reaction dynamics, novel mass-spectrometric methods

View profile for John Crowell
John Crowell

Materials chemistry, surface kinetics of metals/semiconductors, CVD, photo-induced deposition, thin-film spectroscopy.

View profile for John Czworkowski
John Czworkowski

Science and Math Initiative/California Teach; problem-based learning; the use of computer multimedia for science instruction

View profile for Edward Dennis
Edward Dennis

Biochemistry: phospholipase A2, signal transduction in macrophages, lipid maps, prostaglandin regulation, mass spec of lipids and proteins.

View profile for Neal Devaraj
Neal Devaraj

Biomimetic Chemistry, Molecular Imaging, Electrochemistry

View profile for Jack Dixon
Jack Dixon

Protein Tyrosine Phosphatase, Dual=specific Phosphatase, PTEN

View profile for Daniel Donoghue
Daniel Donoghue

Fibroblast Growth Factor Receptors (FGFRs) in Human Cancer

View profile for Pieter Dorrestein
Pieter Dorrestein

Biochemistry, Chemical Biology, Mass spectrometry; Harvesting genomic information for therapeutics.

View profile for Joshua Figueroa
Joshua Figueroa

Inorganic and Organometallic Chemistry: Synthesis, Small Molecule Activation and New Transformations.

View profile for Marye Anne Fox
Marye Anne Fox

Physical organic chemistry; photochemistry; nanoscience of organized arrays.

View profile for Michael Galperin
Michael Galperin

Electron Transport in Condensed Phases. Dissipation and Relaxation Processes. Non-equilibrium Open Quantum Systems. Molecular Electronics.

View profile for Gourisankar Ghosh
Gourisankar Ghosh

Biochemistry and biophysics: transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactions

View profile for Gourisankar Ghosh
Gourisankar Ghosh

Biochemistry and biophysics: transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactions

View profile for Partho Ghosh
Partho Ghosh

Mechanisms of bacterial and protozoan pathogenesis, and host response against infectious microbes.

View profile for Nathan Gianneschi
Nathan Gianneschi

Bioorganic chemistry, Supramolecular Chemistry, Bionanotechnology, Materials, Synthesis

View profile for Carlos Guerrero
Carlos Guerrero

Chemical synthesis; synthesis-oriented organic chemistry; methods development; synthesis design; total synthesis of natural products.

View profile for Thomas Hermann
Thomas Hermann

RNA as a Drug Target.                                                 

View profile for Alexander Hoffmann
Alexander Hoffmann

Biochemistry: signaling, transcription, computational network; stress and immune responses, apoptosis, proliferation

View profile for Patricia Jennings
Patricia Jennings

Biophysical chemistry: protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies

View profile for Simpson Joseph
Simpson Joseph

Molecular Mechanism of Protein Synthesis

View profile for Judy Kim
Judy Kim

Biophysical chemistry: Spectroscopic studies of membrane protein folding and dynamics

View profile for Elizabeth Komives
Elizabeth Komives

Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics

View profile for Clifford Kubiak
Clifford Kubiak

Inorganic, materials, and physical chemistry: electron transfer, catalysis, fixation and utilization of carbon dioxide.

View profile for Andrew Kummel
Andrew Kummel

STM/STS of gate oxides on compound semiconductors and adsorbates on organic semiconductor

View profile for Katja Lindenberg
Katja Lindenberg

Theoretical chemical physics: non-equilibrium statistical mechanics;stochastic processes; nonlinear phenomena; complex systems; condensed matter.

View profile for Douglas Magde
Douglas Magde

Experimental physical chemistry: photochemistry and photobiophysics; pico- and femtosecond lasers

View profile for J. Andrew McCammon
J. Andrew McCammon

Statistical mechanics and computational chemistry, with applications to biological systems

View profile for Mario Molina
Mario Molina

Physical Chemistry: Gas Phase Chemical Kinetics and Photochemistry; Chemistry of Atmospheric Aerosols; Air Pollution in Megacities of the Developing World

View profile for Tadeusz Molinski
Tadeusz Molinski

Organic chemistry of marine natural products, synthesis, NMR, and biomedical applications

View profile for Ulrich Muller
Ulrich Muller

Evolution of catalytic RNAs, and the Origin of Life

View profile for KC Nicolaou
KC Nicolaou

Total Synthesis and Chemical Biology of Natural and Designed Molecules

View profile for Joseph O
Joseph O'Connor

Organotransition metal; organic; physical organic; bioorganometallic; synthetic; and inorganic chemistry

View profile for Stanley Opella
Stanley Opella

NMR structural studies of proteins in membranes and other supramolecular assemblies

View profile for Francesco Paesani
Francesco Paesani

Theoretical chemical physics of complex interfaces of relevance to the environment

View profile for Charles Perrin
Charles Perrin

Physical-organic chemistry: stereoelectronic effects; hydrogen bonding; isotope effects; ionic solvation

View profile for Robert Pomeroy
Robert Pomeroy

The application of analytical chemistry to forensic, environmental and industrial chemistry, then bridge these experiences into the classroom. This also includes the role technology and instrumentation play in discovery and problem solving.

View profile for Kimberly Prather
Kimberly Prather

Environmental, physical/analytical chemistry: gas/particle processes of tropospheric significance; mass spectrometry; laser-based analysis techniques.

View profile for Arnold Rheingold
Arnold Rheingold

Inorganic chemistry: Small-molecule crystallography, synthesis of transition metal/p-block clusters

View profile for Michael Sailor
Michael Sailor

Nanomaterials: porous silicon, chemical and biological sensors, biomaterials, electrochemistry

View profile for Barbara Sawrey
Barbara Sawrey

Chemical education: development of computer-based multimedia to assist student learning of complex scientific processes and concepts

View profile for Amitabha Sinha
Amitabha Sinha

Experimental physical chemistry: photochemistry; laser spectroscopy; reaction dynamics of vibrationally excited molecules

View profile for Michael Tauber
Michael Tauber

Physical chemistry; Optical and magnetic spectroscopy; Fundamental studies of charge transport and solvation; Applications to energy conversion and energy storage.

View profile for Susan Taylor
Susan Taylor

Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily.

View profile for Akif Tezcan
Akif Tezcan

Bioinorganic and biophysical chemistry; Metalloprotein structure, function and biosynthesis; Biomaterials

View profile for Emmanouil Theodorakis
Emmanouil Theodorakis

Synthetic, Medicinal, Bioorganic and Biological Chemistry, Methods and Strategies in Natural Products Chemistry

View profile for Mark Thiemens
Mark Thiemens

Atmospheric chemistry: physical chemistry of isotope effects; solar system formation

View profile for Navtej Toor
Navtej Toor

Structure and Function of Introns and Retroelements

View profile for Yitzhak Tor
Yitzhak Tor

Ligand-nucleic acid interactions; Antiviral and antibacterial agents; Fluorescent nucleosides and nucleotides; Cellular delivery vehicles

View profile for William Trogler
William Trogler

Inorganic chemistry: polymer chemistry; nanomaterials.

View profile for Roger Tsien
Roger Tsien

Chemical biology; design, synthesis, and application of molecular probes of biological function

View profile for Robert Tukey
Robert Tukey

Environmental toxicology: The role of environmental and chemical toxicants on gene expression

View profile for Hector Viadiu
Hector Viadiu

Laboratory of Structural Biochemistry: X-ray Crystallography and Cryo-Electron Microscopy of DNA Binding Proteins and Membrane Proteins

View profile for Wei Wang
Wei Wang

Inference of gene regulatory networks and determination of protein specificity

View profile for John Weare
John Weare

Physical chemistry: calculations of the dynamics of complex systems; theoretical geochemistry

View profile for Haim Weizman
Haim Weizman

Chemical education, Bioorganic chemistry

View profile for James Whitesell
James Whitesell

Organic chemistry: studies of stereochemistry, both in a molecular and a supramolecular sense.

View profile for Roy Wollman
Roy Wollman

Spatio-temporal signaling control of biological self-organization. Signaling networks in innate immunity. Microscopy; Mathematical modeling; Computational image analysis; Systems Biology.

View profile for Jerry Yang
Jerry Yang

Bioorganic Chemistry, Molecular Self-Assembly, Molecular Synthesis, Materials Chemistry, Bionanotechnology


Events and Seminars

Jul 23 2014 at 1:00PM
Thesis Defense
Henry Korman
I. Asymmetric Total Synthesis of Cylindrocyclophanes A and F through Cyclodimerization and a RambergBäcklund Reaction II. Studies Directed Towards the Total Synthesis of CJ-16,264
Jul 24 2014 at 11:00AM
Thesis Defense
Eduardo Caro
Secondary metabolites as potential cancer therapeutic leads: synthesis and chemical biology of Englerin A and Fusarisetin A
Jul 24 2014 at 2:00PM
Thesis Defense
Cheng-Chih "Richard" Hsu
Development of Microscopy Ambient Ionization Top-Down Mass Spectrometry
Aug 7 2014 at 11:00 AM
Inorganic Seminar
Professor Ali Coskun
Directing Structural Features and Gas Sorption Properties of Covalent Amorphous Polymers
Oct 9 2014 at 12:00 pm
Biochemistry Seminar
Professor Tatyana Polenova
Structure and Dynamics of Microtubule-Associated and HIV-1 Protein Assemblies: Insights from Hybrid MAS NMR and Molecular Dynamics Approach
Oct 9 2014 at 12:00 pm
Special Seminar
Professor Tatyana Polenova***2014 Regitze R. Vold Memorial Prize Lecture
Structure and Dynamics of Microtubule-Associated and HIV-1 Protein Assemblies: Insights from Hybrid MAS NMR and Molecular Dynamics Approach
Oct 16 2014 at 12:00 pm
Biochemistry Seminar
Professor David Relman
Explorations of Self: The Human Microbiome in Health and Disease
Oct 23 2014 at 12:00 pm
Biochemistry Seminar
Professor Mark Lemmon
TBA
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