Nathan Gianneschi
Bioorganic chemistry, Supramolecular Chemistry, Bionanotechnology, Materials, Synthesis
Bioorganic chemistry, Supramolecular Chemistry, Bionanotechnology, Materials, Synthesis
Contact Information
Assistant Professor of Chemistry and Biochemistry
Office: Pacific Hall 6224A
Phone: 858-246-0857
Email: ngianneschi@ucsd.edu
Web: http://gianneschigroup.ucsd.edu
Group: View group members
Office: Pacific Hall 6224A
Phone: 858-246-0857
Email: ngianneschi@ucsd.edu
Web: http://gianneschigroup.ucsd.edu
Group: View group members
Education
2005 PhD, Chemistry, Northwestern University, IL
1999 B.Sc, Chemistry (Hons), University of Adelaide, Australia
2005 PhD, Chemistry, Northwestern University, IL
1999 B.Sc, Chemistry (Hons), University of Adelaide, Australia
Appointments
2008 Postdoc, Postdoctoral fellow, The Scripps Research Institute
2008 Postdoc, Postdoctoral fellow, The Scripps Research Institute
Awards and Academic Honors
2012
NIH Director's Transformative Research Award
2012
Alfred P. Sloan Research Fellow
2011
UCSD Panhellenic Outstanding Professor Award
2011
Royal Society of Chemistry Emerging Investigator
2011
NIH Director's New Innovator Award
2009
Presidential Early Career Award for Scientists and Engineers
2008
Camille and Henry Dreyfus Foundation New Faculty Award
2006
ACS Young Investigator Award - Division of Inorganic Chemistry
2005
Dow Chemical Company Foundation Postdoctoral Fellow
Research Interests
The ability to control the assembly and destruction of nanoscale materials in response to specific biomolecular stimuli is expected to have a significant impact in targeted drug delivery and advanced sensor design. Our program takes a multidisciplinary approach to the development of novel, stimuli responsive supramolecular and nanoscale materials by combining synthetic organic and inorganic chemistry with biological molecules and polymers.
Primary Research Area
Organic Chemistry
Organic Chemistry
Interdisciplinary interests
Bioorganic
Materials
Materials
Selected Publications
- Rush, A.M.; Thompson, M.P; Tatro, E.T.; Gianneschi, N.C. "Nuclease Resistant DNA via High Density Packing in Polymeric Micellar Nanoparticle Coronas" ACS Nano, (2013), 7, 1379-1387
- Chien, M.-P.; Thompson, M. P.; Lin, E. C.; Gianneschi, N. C. "Fluorogenic enzyme-responsive micellar nanoparticles" Chem. Sci. (2012), 3, 2690-2694
- Chien, M. -P.; Gianneschi, N. C. "A Morphology-Dependent Bioorganic Template for Inorganic Nanowire Synthesis." Small (2011), 7, 2041-2046
- Chien, M.-P.; Thompson, M. P.; Gianneschi, N. C."DNA-nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes"ChemComm, (2011), 47, 167-169.
- Ku, T.-H.; Chien, M.-P.; Thompson, M. P.; Sinkovits, R. S.; Olson, N. H.; Baker, T. S.; Gianneschi, N. C. "Controlling and Switching the Morphology of Micellar Nanoparticles with Enzymes" J. Am. Chem. Soc. (2011), 133, 8392-8395
- Chien, M. -P.; Rush, A.M.; Thompson, M.P.; Gianneschi, NC. "Programmable Shape-Shifting Micelles" Angew. Chem. Int. Ed., (2010), 49, 5076-5080
- Rubinshtein, M.; James, C. R.; Young, J. L.; Ma, Y. J.; Kobayashi, Y.; Gianneschi, N. C.; Yang, J. "Facile Procedure for Generating Side Chain Functionalized Poly(a-hydroxy acid) Copolymers from Aldehydes via a Versatile Passerini-Type Condensation" Organic Letters (2010), 12, 3560-3563
- Thompson, M.P.; Chien, M.-P.; Ku, .T.-H.; Rush, A.M.; Gianneschi, N.C. "Smart Lipids for Programmable Nanomaterials" Nano Letters, (2010), 10, 2690-2693