Inorganic chemistry: polymer chemistry; nanomaterials.
Ph.D., , California Institute of Technology
M.A., , Johns Hopkins
B.A., , Johns Hopkins
Awards and Academic Honors
Elected Fellow of the American Association for the Advancement of Science
Alfred P. Sloan Fellow
Rohm and Haas Faculty Fellow
DuPont Young Faculty Fellow
Phi Beta Kappa
Research focuses on new inorganic materials for chemical, biological and environmental sensing. One project focuses on the synthesis of new photoluminescent and electroluminescent silole and silafluorene trimers (Figure 1) and conjugated polymers. These materials are being applied to detecting high explosives and environmental toxicants by fluorescence methods. This enables detection of trace particles of explosives, which have applications in forensics.
There is a need for the development of inexpensive portable electronic devices for the specific detection of toxic chemicals, such as terrorist nerve agents, as well as for monitoring gaseous pollutants. In current collaborative research with professors Kummel (Chemistry) and Schuller (Physics), we are exploring physical vapor deposition of discrete transition metal complexes, as well as solution deposition methods, to construct chemical field effect transistors that function as chemical sensors. This research involves the synthesis of robust metal complexes that can be solution deposited as nanoscale films across electrodes for sensing in a chemFET configuration. Surface metal coordination of the vapor analyte controls the electronic sensor response.
In addition, we are exploring template approaches for preparing uniform hollow silica and titania nanospheres in the 100-3000 nm range (Figure 2) for ultrasonic imaging and cell sensor applications. The recent work has generated broad interest and is becoming increasingly cited.
Primary Research Area
- Liberman A, Martinez HP, Ta CN, Barback CV, Mattrey RF, Kono Y, Blair SL, Trogler WC, Kummel AC, Wu Z, "Hollow silica and silica-boron nano/microparticles for contrast-enhanced ultrasound to detect small tumors.", Biomaterials, 2012, 20, 5124-9
- Pohaku Mitchell KK, Liberman A, Kummel AC, Trogler WC, "Iron(III)-doped, silica nanoshells: a biodegradable form of silica.", J Am Chem Soc, 2012, 34, 13997-4003
- Royer JE, Zhang C, Kummel AC, Trogler WC, "Air-stable spin-coated naphthalocyanine transistors for enhanced chemical vapor detection.", Langmuir, 2012, 14, 6192-200
- Sandoval S, Yang J, Alfaro JG, Liberman A, Makale M, Chiang CE, Schuller IK, Kummel AC, Trogler WC, "Europium Doped TiO(2) Hollow Nanoshells: Two-Photon Imaging of Cell Binding.", Chem Mater, 2012, 21, 4222-4230
- Yang J, Sandoval S, Alfaro JG, Aschemeyer S, Liberman A, Martin DT, Makale M, Kummel AC, Trogler WC, "Red-luminescent europium (III) doped silica nanoshells: synthesis, characterization, and their interaction with HeLa cells.", J Biomed Opt, 2011, 6, 066012
- Martinez HP, Kono Y, Blair SL, Sandoval S, Wang-Rodriguez J, Mattrey RF, Kummel AC, Trogler WC, "Hard shell gas-filled contrast enhancement particles for colour Doppler ultrasound imaging of tumors.", Medchemcomm, 2010, 4, 266-270
- Yang J, Aschemeyer S, Martinez HP, Trogler WC, "Hollow silica nanospheres containing a silafluorene-fluorene conjugated polymer for aqueous TNT and RDX detection.", Chem Commun (Camb), 2010, 36, 6804-6
- Sanchez JC, Trogler WC,"Hydrosilylation of Diynes as a Route to Functional Polymers Delocalized Through Silicon," Macromol. Chem. Phys.,(2008), 209, 1527-1540.
- Sanchez JC,Trogler, WC,"Efficient blue-emitting silafluorene/fluorene-conjugated copolymers: selective turn-off/turn-on detection of explosives,"J. Mater. Chem., (2008), 18, 3143-3156.
- Yang J, Lind JU, Trogler WC, "Synthesis of Hollow Silica and Titania Nanospheres," Chem. Mater., (2008), 20, 2875-2877.