Michael Sailor
Nanomaterials: porous silicon, chemical and biological sensors, biomaterials, electrochemistry
Contact Information
Office: PACH 4140
Phone: (858) 534-8188
Fax: (858) 534-5383
Email: msailor@ucsd.edu
View group members

Education and Appointments
1988 Ph.D., Northwestern University
1983 B.S., Harvey Mudd College

Awards and Academic Honors
2006 Bronze Phantom Award recipient from the Boeing Company, Phantom Works Division
2004 Outstanding Faculty Mentor in the Sciences and Engineering, UC San Diego Faculty Mentor Program
2003 Grand Prize, National Inventors Hall of Fame Collegiate Inventors Competition (shared with graduate student Jamie R. Link)
2002 Popular Science Magazine "Best of What's New" General Technology award winner
1995 University of California Presidential Award for Excellence in Undergraduate Research
1994-1995 Alfred P. Sloan Research Fellow
1994 Camille Dreyfus Teacher-Scholar
1993-1998 NSF Young Investigator Award
1993 Arnold and Mabel Beckman Young Investigator Award
1988-1990 Postdoctoral position, Stanford University and California Institute of Technology

Research Interests
Research in the Sailor group involves the chemistry, electrochemistry, and photophysics of nanophase semiconductors, with emphasis on photonic crystals, superparamagnetic iron oxide nanoparticles, molecular sensors, and biomaterials. Our research focuses on applications in medical diagnostics, drug delivery, cancer treatment, high-throughput screening, and low-power sensing of environmental toxins, pollutants, and chemical or biological warfare agents.
Primary Research Area: Interdisciplinary Specialties:
Inorganic Chemistry Materials
Atmospheric and Environmental


Image Gallery:
Figure 1: Magnetic, amphiphilic porous silicon microparticles used to carry and deliver nanoparticle, biomolecule, or drug payloads. Image: Liz Wu Figure 2: This cross-sectional electron microscope image displays the porous nanostructure that was generated using a current-time etching waveform, depicted at the left. Image: Shawn O. Meade
Figure 3: Gradient photonic crystal etched into silicon. The porous silicon chip is used in sensing of pollutants and environmental toxins. Image: Adrian Garcia Sega

Selected Publications
  • Maltzahn, G. v.; Harris, T. J.; Park, J.-H.; Schmidt, A. J.; Sailor, M. J.; Bhatia, S. N., Nanoparticle Self-Assembly Gated by Logical Proteolytic Triggers. J. Am. Chem. Soc. 129, 6064-6065 (2007).
  • Thomas, J. C.; Pacholski, C.; Sailor, M. J., Delivery of Nanogram Payloads Using Magnetic Porous Silicon Microcarriers. Lab Chip 6, 782 - 787 (2007).
  • Schwartz, M. P.; Derfus, A. M.; Alvarez, S. D.; Bhatia, S. N.; Sailor, M. J., The smart petri dish: A nanostructured photonic crystal for real-time monitoring of living cells. Langmuir 22, 7084-7090 (2006).
  • Park, J.-H.; Derfus, A. M.; Segal, E.; Vecchio, K. S.; Bhatia, S. N.; Sailor, M. J., Local Heating of Discrete Droplets Using Magnetic Porous Silicon-Based Photonic Crystals. J. Am. Chem. Soc. 128, 7938-7946 (2006).
  • Orosco, M. M.; Pacholski, C.; Miskelly, G. M.; Sailor, M. J., Protein-coated porous silicon photonic crystals for amplified optical detection of protease activity. Adv. Mater.18, 1393-1396 (2006).
  • Sailor, M. J.; Link, J. R., Smart Dust: nanostructured devices in a grain of sand. Chem. Commun.1375-1383 (2005).
  • Schwartz MP, Alvarez SD, Sailor MJ, "Porous SiO2 interferometric biosensor for quantitative determination of protein interactions: binding of protein A to immunoglobulins derived from different species." Anal Chem 1(327-34): , 2007. [Go to PubMed]
  • King, B. H.; Ruminski, A. M.; Snyder, J. L.; Sailor, M. J., Optical fiber-mounted porous silicon photonic crystals for sensing of organic vapor breakthrough in activated carbon. Adv. Mat. 2007, 19, 4530 - 4534.
  • Segal, E.; Perelman, L. A.; Cunin, F.; Renzo, F. D.; Devoisselle, J.-M.; Li, Y. Y.; Sailor, M. J., Confinement of Thermoresponsive Hydrogels in Nanostructured Porous Silicon Dioxide Templates. Adv. Funct. Mater. 2007, 17, 11531162.
  • Meade, S. O.; Sailor, M. J., Microfabrication of freestanding porous silicon particles containing spectral barcodes. Phys. Status Solidi-Rapid Res. Lett. 2007, 1, (2), R71-R73.