Corbett, Kevin
Molecular mechanisms of recombination and chromosome segregation in meiosis and mitosis

Contact Information
Associate Professor, UCSD Dept. of Cellular and Molecular Medicine

Office: CMM/E
Phone: 858-534-7267
Email: kcorbett@ucsd.edu
Web: corbettlab.org
Education
2005 PhD, Molecular Cell Biology, University of California, Berkeley
2000 BS, Biochemistry, University of Virginia
Research Interests
Our laboratory is focused on the molecular mechanisms of chromosome segregation in mitosis and meiosis. We use biochemistry, X-ray crystallography, and cryo-electron microscopy to probe the structure, function, and interactions between proteins involved in meiotic chromosome pairing, crossover initiation and maturation, and chromosome segregation. We also study a novel second messenger-based bacteriophage immunity pathway in bacteria, that incorporates eukaryotic-like HORMA domains in a foreign protein-sensing role.
Interdisciplinary interests
Biophysics
Macromolecular Structure
Cellular Biochemistry


Selected Publications