Budin, Itay
Biochemistry and synthetic biology of cell membranes
Education
2012 PhD,
Harvard University
2007 BS,
Cornell University
Awards and Academic Honors
2023
Walter A. Shaw Young Investigator Award
2022
DOE Early Career Award
2020
NSF CAREER Award
2019
Early Career Board Member, JBC
2017
Herb Tabor Young Investigator Award
2012
Miller Institute Junior Fellowship
2012
Harold M. Weintraub Award
2009
Matt Meselson Prize
Research Interests
The Budin Lab uses biophysical, engineering, and chemical approaches to understand the inner workings of cell membranes and their lipid building blocks.
Primary Research Area
Biochemistry
Interdisciplinary interests
Cellular Biochemistry
Biophysics
Selected Publications
- Winnikoff JR,Haddock SHD,Budin I "Depth- and temperature-specific fatty acid adaptations in ctenophores from extreme habitats.", J Exp Biol, 2021, Vol. 224, Issue 21,
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- Brenac L,Baidoo EEK,Keasling JD,Budin I "Distinct functional roles for hopanoid composition in the chemical tolerance of Zymomonas mobilis.", Mol Microbiol, 2019,
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- Budin I,Keasling JD "Synthetic Biology for Fundamental Biochemical Discovery.", Biochemistry, 2019, Vol. 58, Issue 11, 1464-1469
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- Budin I,de Rond T,Chen Y,Chan LJG,Petzold CJ,Keasling JD "Viscous control of cellular respiration by membrane lipid composition.", Science, 2018, Vol. 362, Issue 6419, 1186-1189
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- Degreif D,de Rond T,Bertl A,Keasling JD,Budin I "Lipid engineering reveals regulatory roles for membrane fluidity in yeast flocculation and oxygen-limited growth.", Metab Eng, 2017, Vol. 41, 46-56
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- Budin I,Prwyes N,Zhang N,Szostak JW "Chain-length heterogeneity allows for the assembly of fatty acid vesicles in dilute solutions.", Biophys J, 2014, Vol. 107, Issue 7, 1582-90
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- Budin I,Debnath A,Szostak JW "Concentration-driven growth of model protocell membranes.", J Am Chem Soc, 2012, Vol. 134, Issue 51, 20812-9
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- Budin I,Devaraj NK "Membrane assembly driven by a biomimetic coupling reaction.", J Am Chem Soc, 2012, Vol. 134, Issue 2, 751-3
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- Budin I,Szostak JW "Physical effects underlying the transition from primitive to modern cell membranes.", Proc Natl Acad Sci U S A, 2011, Vol. 108, Issue 13, 5249-54
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- Budin I,Szostak JW "Expanding roles for diverse physical phenomena during the origin of life.", Annu Rev Biophys, 2010, Vol. 39, 245-63
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- Budin I,Bruckner RJ,Szostak JW "Formation of protocell-like vesicles in a thermal diffusion column.", J Am Chem Soc, 2009, Vol. 131, Issue 28, 9628-9
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